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Description
It is an aromatase inhibitor primarily used to treat certain forms of breast cancer in women who are in the post-menopausal phase. Act by reducing the amount of estrogen.
What is Aromasin?
It is a drug produced by Pfizer India Ltd., a division of Pfizer Inc., one of the world’s largest pharmaceutical companies. The Company has a remarkable presence in India, its corporate office in Mumbai, and multiple manufacturing sites throughout the country. Pfizer India focuses on curative areas such as cardiology, oncology, neurology, endocrinology, and vaccines.
Aromasin Pfizer, having exemestane as its active ingredient, is often utilized to treat post-menopausal women with breast cancer. It belongs to the category of aromatase inhibitors, which lower the body’s estrogen levels because many breast tumors grow more quickly when estrogen is high.
Pfizer’s Aromasin price, in comparison to the generic version, ranges from $200 to $400 for a 30-day supply.
Which Medical Conditions are Treated by Aromasin?
This medicine is typically advised for:
Breast Cancer
In postmenopausal women, it is used to treat estrogen-receptor-positive (ER-positive) breast cancer in both early and advanced stages. This medication is prescribed to patients who have already received radiation therapy, surgery, or other cancer therapies.
Bodybuilding
Although not prescribed, some bodybuilders use it off-label to manage estrogen levels and reduce side effects such as gynecomastia and water retention associated with anabolic steroid use. Aromasin for men is not recommended.
Guidelines for Use
Dosage
The typical dosage is one 25 mg pill, once daily, just after eating.
Administration
- Take the medicine at the same time daily.
- Swallow it entirely along the water.
- It is essential to adhere to the recommended regime without skipping any doses. If you miss a dose, take it as soon as you remember.
Treatment duration may vary depending on each patient’s unique medical condition and therapy response. Your healthcare professional will decide the right course of treatment.
Liver and Kidney function
Patients with liver or kidney disease should use it only with the advice of a doctor.
Monitoring
To increase the efficacy of the medicine and manage side effects, be in touch with your healthcare provider.
How Does Aromasin Work?
Aromatase is an enzyme involved in estrogen synthesis, and this medicine inhibits it. It dramatically reduces the body’s estrogen levels by inhibiting enzymes. Reducing estrogen levels helps to slow down or halt the growth of breast cancer cells.
Duration of Therapy
The stage and type of breast cancer determine how long the therapy will last. It is typically recommended for five years, although the exact duration should be decided by a doctor based on each patient’s needs and response to the treatment.
Side Effects
Common Side Effects:
The side effects of medicine are generally tolerable, but some people may experience the following:
- Hot flashes
- Exhaustion
- Headaches
- Joint Discomfort
- Insomnia
- Increased perspiration
- Nausea
- Osteoporosis
- Increased Appetite
- Depression and Anxiety
Serious Side Effects:
Some individuals may experience severe side effects like:
- Alterations in liver function, jaundice, and elevated liver enzymes.
- Serious allergic responses like rash, itching, swelling, and difficulty breathing.
- Excruciating chest pain or dyspnea.
- Heart Problems such as high blood pressure and increased cholesterol levels.
Management of Side Effects:
Managing the Aromasin side effects includes many lifestyle changes, supportive changes, and medical interventions.
- Hot Flashes:
Wear light clothing, keep calm, and use fans.
- Joint Pain:
Over-the-counter pain relievers and consistent exercise can be helpful.
- Bone Health:
Ensure you’re getting sufficient and do weight-bearing workouts.
Guidelines for Storing Aromasin
- Keep it between 20°C and 25°C (68°F and 77°F) at room temperature.
- Store the drug in its original container, shielded from light and moisture.
- Ensure it stays out of reach of children.
Precautions and Warnings
- Allergic Reactions: Let your doctor know if you have ever had an adverse reaction to exemestane or any other medication.
- Bone Density: Due to the high risk of osteoporosis, regular bone density screenings are advised.
- Pregnancy and Breastfeeding: Premenopausal women, as well as those who are expecting or nursing, should not take this medicine.
- Liver Function: Liver patients use it cautiously.
Drug Interactions
When the medicine interacts with other drugs, it may not work as intended or may cause more severe side effects. Inform your doctor about all of the medication you take, with specific attention to:
Products containing estrogen can reduce the effectiveness of the medicine. Patients should avoid such medicines.
CYP3A4 Inducers decrease plasma concentrations of Aromasin, reducing its efficacy. Examples include
- Rifampin ( an antibiotic)
- Phenytoin ( an anticonvulsant)
- Carbamazepine ( used for epilepsy and bipolar disorder)
- Anticoagulants
- Specific blood pressure drugs
Conclusion
For postmenopausal women, Pfizer Aromasin (exemestane) is an essential drug in the fight against estrogen-receptor-positive breast cancer. Patients can effectively manage their treatment by being aware of its use, possible adverse effects, and required precautions. To be sure about this medicine, it is the best option for your situation, and to obtain individualized guidance throughout the therapy, always see a healthcare professional.
FAQs
Can Men Take Aromasin?
It is mainly used to treat post-menopausal women for breast cancer, but some men in the bodybuilding community use it off-label to manage estrogen-related side effects from anabolic steroids. Aromasin bodybuilding dosage for men ranges from 12.5 mg to 25 mg every other day. The right amount depends upon the amount of anabolic steroids taken and the person’s health.
What Should I Avoid While Taking Aromasin?
Utilizing any estrogen-containing products, such as hormone replacement treatment or specific herbal products, reduces the effectiveness of the medicine.
Is Aromasin the Same as Arimidex?
Both Arimidex and Aromasin are aromatase inhibitors used in the treatment of breast cancer.
Aromasin vs Arimidex
- Active Ingredients:
Their active components differ. Aromasin contains exemestane, and Arimidex contains anastrozole.
- Mechanism of Action:
Aromasin (Exemestane) is a steroidal aromatase inhibitor that binds to the aromatase enzyme irreversibly, resulting in a permanent reduction in estrogen production. In contrast, Arimidex (Anastrozole) binds reversibly to the aromatase enzyme, leading to a temporary reduction in estrogen level. It is a non-steroidal aromatase inhibitor.
- Effects:
Aromasin has more lasting effects on estrogen levels. In contrast, Arimidex effects are reversible and can be more easily adjusted.
What Does Aromasin Do for Bodybuilders?
When using anabolic steroids, some bodybuilders utilize this drug to control their estrogen levels. However, there could be consequential hazards and adverse effects, and aromasin for men is not recommended.
Does Aromasin Make You Lose Weight?
One of the uncommon side effects of this drug is weight loss. While taking this drug, some patients may gain weight or have trouble controlling their weight.
Where Can I Buy Aromasin?
The patients can buy it with a prescription. If your doctor has given you a valid prescription, you can buy it at most pharmacies. Additionally, several web platforms like arrowmeds.com make aromasin buy accessible, guaranteeing convenience for people nationwide. You ensure the product’s authenticity and quality and make sure you purchase from a reliable vendor.
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