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Description
What is Celkeran 2 Mg?
Celkeran 2 mg is a medication that is used to treat cancer. It is prescribed by the doctors for certain kinds of cancers during chemotherapy. It is a prescription medicine which is taken orally. This chemotherapy drug falls under a group of drugs commonly known as alkylating agents.
Celkeran 2 mg is the brand name for the drug called Chlorambucil. It is marketed and distributed by Celon Laboratories Pvt. Ltd. which is a biopharmaceutical business that specializes in creating cost-effective, innovative, and non-infringing solutions and serves both the Indian and ROW markets while upholding international quality standards.
What is Celkeran 2 Mg used for?
Celkeran 2 mg is a medication containing the active ingredient Chlorambucil that is primarily used for the treatment of a certain kind of blood cancer known as CLL or chronic lymphocytic leukemia. When used for blood cancer, it disrupts the natural growth as well as the multiplication of the cancer cells.
It is also used for the treatment of Hodgkin’s disease, a blood cancer that occurs in the lymphatic system. The immune system fights infections and eliminates waste with the aid of the lymphatic system. While used for Hodgkin’s disease, it stops the cancer cell growth in the lymphatic system.
Apart from that it may also be prescribed for non-Hodgkin’s lymphoma. Apart from that it might be prescribed for other purposes as determined by a doctor. For example, it is often used as an immunosuppressive drug as well by doctors for certain conditions like nephrotic syndrome.
How to use Celkeran 2 Mg?
Celkeran 2 mg is an oral route medicine. Hence, you should swallow the tablet as a whole with a glass of water. Do not mess with the tablet by trying to break it in half or chew it. Generally, it is taken on an empty stomach. However, the proper way to take the medicine can be determined by your doctor only.
What does Celkeran 2 Mg do?
Celkeran 2 mg is an anti-cancer medicine that primarily works by stopping the growth of cancer cells. It further enhances its effectiveness by restricting the multiplication of the cancer cells. In simple terms, it damages the DNA and RNA of the cancer cells. To describe in a bit more technical terms, its mechanism of damaging DNA and stopping the growth and multiplication of cancer cells can be broken down into three steps:
- It binds DNA bases to alkyl groups. This stops DNA synthesis and RNA transcription from the damaged DNA by causing repair enzymes to break up the DNA in their attempts to replace the alkylated bases.
- It damages DNA by the creation of cross-links that stop DNA from being separated for transcription or synthesis.
- It induces nucleotide impairment that results in mutations.
The recommended dosage of Celkeran 2 Mg
Celkeran 2 mg is a common dosage that is prescribed to many patients. But you must not choose the dosage on your own by reading recommendations on any website.
The proper dosage for you can be properly determined only by the doctor under whom your diagnosis is going on. If the doctor thinks so, s/he may also prescribe Celkeran 5 mg, which is another dosage of the same tablet.
Missed Dose:
If you somehow miss a dose, firstly, you must not panic. You should take the tablet as soon as you remember. However, if it is too late and almost time for the next dose, you should skip the current dose and continue with the next as regular.
Overdose:
Overdose may cause some side effects which may be mild as well as, oftentimes, may be serious. Hence, if you are observing serious side effects, you should stop taking the medicine and contact your doctor immediately.
How to Store Celkeran 2 Mg?
You should store the tablet in a dry and cool place, ideally below 2 – 8°C. Avoid freezing the tablet. Keep the tablet out of the reach of children and animals.
Potential Side Effects
Celkeran 2 mg tablets may have possible side effects. While in some people side effects are mild and are considered common, some others show serious side effects. Below are the side effects of this tablet:
Common Side Effects:
Serious Side Effects:
- Skin rash
- Unusual bruising or bleeding
- Black, tarry stools
- Red urine
- Cough
- Sore throat
- Congestion
- Fever
- Difficulty breathing
- Seizures
- Yellowing of the skin or eyes
- Pain in the upper right part of the stomach
- Dark colored urine
- Frequent urination
- Unusual lumps or masses
Precautions and Contraindications
You should take some precautions beforehand so that you can stay free from any risks. You should follow the below tips while using this medicine:
- If you are allergic to other alkylating agents (namely cyclophosphamide, bendamustine, ifosfamide, busulfan, carmustine, procarbazine, lomustine, melphalan, or temozolomide), you should also tell your doctor.
- If you are allergic to Chlorambucil itself, you must tell your doctor about it. Otherwise, you will observe allergic reactions in your body.
- If you are pregnant (or planning to get pregnant in the near future) or breastfeeding, you must inform your doctor.
- You should not accept any kind of vaccine without asking your doctor while you are on the course of Chlorambucil.
- Let your doctor know what prescription and non-prescription medications you are taking so that the doctor can detect whether you are taking any drug that may interact with Chlorambucil.
- Let your doctor know about your past medical history. Also if you are supposed to have any surgery in the near future, tell your doctor about this too.
- If you have gone through chemotherapy or radiation therapy in the last 1 month, tell your doctor before continuing with Celkeran 2 mg.
- If you have any past history of seizure or head injury, tell your doctor about it.
- You should avoid alcohol, or at least restrict the consumption of alcohol to a great extent.
Conclusion
Celkeran 2 mg is a chemotherapy medication that is used for the treatment of certain kinds of blood cancers and Hodgkin’s lymphoma. If you are taking this medication, abide by the dosage and duration that your doctor has recommended you. Also, you should keep in mind the possible side effects that you may encounter while using this drug. Do not forget to take the necessary precautions beforehand to remain in a risk-free zone.
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