Alternative Medicine

Palbace 125 mg (Palbociclib)

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Just £77.52 /Capsules View Detail This product has multiple variants. The options may be chosen on the product page

Palbociclib (Palbociclib)

Rated 0 out of 5

Just £3.93 /Capsules View Detail This product has multiple variants. The options may be chosen on the product page

Description

What is Piclib 125 mg?

Piclib 125 is an oral medicine which is a part of the class of anticancer drugs known as cyclin-dependent kinase inhibitors. Oncologists often suggest this drug for treating breast cancer.

Cancer is a chronic condition in which cancer cells multiply and grow inside the body in an abnormal manner. This form of breast cancer is marked by the lack of HER2 gene amplification and the presence of estrogen or progesterone receptors.

For the treatment of breast cancer, Piclib 125 mg is recommended to patients in combination with some other anticancer medications.

Patients will be advised to take this drug if cancer cell has spread to other parts. This is a targeted therapy that contains the active ingredient palbociclib. Hetero Drugs Ltd manufactures this medicine precisely in capsule form.

What is Piclib 125mg used for?

It is a suitable medicine that is prescribed to breast cancer patients in their initial treatment. Piclib drug is an effective drug that is given to patients who have hormone receptor-positive, advanced-stage breast cancer. This is a type of breast cancer that depends on hormones like estrogen to grow and spread in the body. This type of cancer is a generalized cancer that metastasizes.

Palbociclib, the active ingredient of this drug, falls under the category of medications called kinase inhibitors. The mechanism of action of this key ingredient involves blockage of the abnormal protein that signals the cancerous cells in the body.

These signals enable the cells to multiply and grow uncontrollably in the body. As a result of this, this medicine is able to stop or slow down the spread of dangerous cancerous cells. This medication is mostly advised in combination with another medication for better results.

Piclib 125mg should always be prescribed in combination with any of these medicines:

• Fulvestrant- It is given to patients with disease progression after completion of the endocrine therapy
• An aromatase inhibitor- This is given for initial endocrine-based therapy in postmenopausal women or in men. This includes anastrozole, exemestane, or letrozole.

How to use Piclib 125mg?

This drug is for oral administration. It comes as a capsule that can be taken by mouth with a glass of water. Doctors advise patients to take this medicine once daily at the beginning of the treatment, the first 21 days of a 28-day cycle. The next 7 days will be without the treatment.

Palbociclib drug can be administered orally with or without food. Try to take this drug daily at the same time, since it maximizes the chances of effectiveness. Number of doses will be prescribed by your healthcare provider.

Your doctor advises you on the dosage and other instructions after understanding your health conditions. So, never take more or less or take it more often than directed by the doctor.

Swallow the capsules as a whole without opening, splitting or chewing them. Also, don’t take capsules that are damaged. In case you vomit the medicine, don’t double up the dosage. Just continue with the next dose.

Your healthcare provider might reduce the dosage or stop your treatment, either temporarily or permanently, in case of certain adverse effects. Always consult with your healthcare provider about how you are feeling when taking this medicine.

How does Piclib 125 mg work?

Piclib 125 mgis given to the patients together with hormonal anticancer therapies and other anticancer medicines.

Piclib Capsule is an anti-cancer medication or antineoplastic agent that inhibits cancer cell proliferation and growth. This happens by inhibiting cyclin-dependent kinases 4 and 6 within neoplastic cells. So, the medicine blocks cyclin-dependent kinases 4 and 6, putting a stop to the whole cycle at one point, which is the growth process of the cancer cell.

CDK 4 and CDK 6 are proteins that trigger the proliferation and division of the cancerous cells in the body. Piclib 125 has a blocking effect on these proteins. This results in an inhibitory impact on cancerous growth and the killing of cells. Piclib drug will also target the estrogen receptor-positive breast cancer cells by blocking the cell cycle.

Side effects of Piclib 125 mg

Piclib drugs may cause a few side effects in some patients because their bodies don’t adjust to the medication. But these effects are very mild and will go away after a few days. Consult your healthcare provider if these effects are serious and causing trouble. Some of these common effects are:

• Fatigue
• Anemia (low number of red blood cells)
• Infection
• Hair loss
• Decreased blood cells
• Rash
• Vomiting
• Fever
• Decreased white blood cell count
• Diarrhea
• Nausea
• Stomatitis is a condition causing inflammation of the mouth
• Weakness
• Decreased appetite

Contraindications

Hypersensitivity:

Those who are allergic to Piclib or any of its components should avoid taking this medication. Tell your doctor, and they may adjust the dose or change the treatment.

Pregnancy:

Piclib 125 mg may be unsafe for pregnant women and their unborn baby. Consult your doctor so that they can advise you to get the right treatment.

Breastfeeding:

Those who are breastfeeding should avoid taking Piclib 125 mg due to possible hazards to the infant. So, talk to the healthcare provider to get the right consultation.

Precautions and Warnings

Piclib 125 mg should be avoided to be administered to patients with serious lung problems. Tell your doctor if you have any lung diseases before starting the Piclib to avoid any complications or side effects.

Alcohol:

Patients taking this drug should avoid alcohol as it may increase the side effects or slow down the effect of Piclib.

Driving:

Intake of Piclib 125 mg capsule can cause tiredness and dizziness. So, avoid driving if you are feeling unwell and seeing these symptoms.

Conclusion

Piclib 125 mg is an effective treatment that doctors suggest for hormone receptor-positive, HER2-negative breast cancer. This is used in combination with other therapies and cancer medicines. This anti-cancer drug works by inhibiting cyclin-dependent kinases, which help to stop the growth of cancer cells. While it offers various benefits, it may cause some mild side effects like fatigue, infection, and anemia. Patients should follow given dosages and consult their healthcare provider on a regular basis to manage any adverse effects.