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Description
What is Tenvir?
Tenvir is an antiviral drug produced by Cipla Limited, one of the leading pharmaceutical companies in the world, known for manufacturing affordable medicines for various health conditions.
It is well-known for its role in producing and distributing low-cost anti-retroviral drugs for HIV/ AIDS.
It is primarily used to treat and manage HIV infection as well as chronic hepatitis B virus(HBV)Tenofovir, the active component of Tenvir, is a part of the nucleotide reverse transcriptase inhibitor (NRTI) drug class.
This drug aids in lowering the body’s viral load, enhancing immune system performance, and reducing the risk of consequences from HIV.
Composition
Tenofovir disoproxil fumarate, or 300 mg of tenofovir, is the active component of Tenvir. It contains several inactive ingredients, including magnesium stearate, lactose monohydrate, croscarmellose sodium, and microcrystalline cellulose. These components assist in the tablet’s production alongside the active ingredient.
What is Tenvir Used For?
It is prescribed primarily for two purposes:
Infection with HIV:
When taken in conjunction with other antiretroviral drugs, it is used to treat HIV-1 infection in adults and adolescents 12 years of age and older. There is no cure for HIV, but its management is possible by lowering the viral load in the body and strengthening the immune system.
Hepatitis B Virus (HBV) Infection That Is Chronic:
It is also for adult patients with persistent HBV infection. It reduces the body’s HBV levels, which lessens liver damage and slows the advancement of liver disease.
This medicine should be taken under the guidance of a healthcare provider. This medication doesn’t cure HIV or HBV, but it helps manage these infections.
How to Take Tenvir?
- Take Tenvir tablet exactly as prescribed by a physician.
- The standard dosage is one 300 mg pill once a day, with or without food.
- Take the medication at the same hour every day to ensure that the dosage stays consistent.
- Put the medication down completely and sip some water. Never break, chew, or crush the tablet.
Mechanism of Action
Tenofovir, the active component of Tenvir, is a NRTI, or nucleotide reverse transcriptase inhibitor. It functions by preventing reverse transcriptase, an enzyme required for HIV and HBV replication. Tenofovir lowers the quantity of virus in the body by preventing the virus from reproducing and inhibiting this enzyme. In addition to improving immune system performance, this activity helps impede the spread of HIV and HBV infections.
Indications and Usage
HIV Infection:
Tenvir, when combined with other antiretroviral drugs, is advised for the treatment of HIV-1 infection in adults and adolescents 12 years of age and above. To manage HIV, it is a component of a comprehensive treatment approach that also includes other drugs, routine monitoring, and lifestyle modifications.
Persistent Hepatitis B Virus (HBV):
Adults with persistent HBV infection who show signs of liver inflammation and active viral replication should also consider Tenvir as a therapy option. It slows the development of liver disease and additional liver damage by lowering the viral load in the liver
Recommended Dosage
Infection with HIV: One 300 mg tablet once daily is the recommended dosage of this drug for treating HIV infection in adults and adolescents.
Persistent HBV Infection: The recommended dosage for persistent HBV infection is one 300 mg tablet daily.
Missed Dose
Take the missed dose as soon as you remember it, but try not to miss any. When your next dose is almost here, skip the one you missed and take your usual dosage as usual.
Overdose
Get medical assistance right away if you overdose on the medicine.
Patients with renal impairment might need to change their dosage depending on their renal function. It’s critical to adhere to the dosage recommendations made by a medical practitioner.
Contraindications
- Those with a history of recognized hypersensitivity to tenofovir or any other ingredient in the formulation should not use this medicine.
- This drug should not be used by patients who have severe renal impairment (creatinine clearance < 30 mL/min).
- Patients having a history of allergic reactions to similar medications should not start this medication. They should inform their healthcare provider about it.
- Although Tenvir is used for Hepatitis B, it must be used carefully in patients coinfected with Hepatitis B and C.
Warnings and Precautions
- This medicine has been associated with potentially fatal lactic acidosis and severe hepatomegaly with steatosis. Patients displaying any of these symptoms should be monitored closely.
- Renal impairment may occur or worsen with tenofovir. During Tenvir treatment, it is advised to regularly assess renal function, particularly in patients with kidney disease.
- Bone mineral density decrease has been linked to tenofovir. Individuals susceptible to osteoporosis or fractures should be closely watched, and they might need to take supplements of calcium and vitamin D.
- Hepatic Flares in Patients with HBV Infection: Patients with HBV infection may experience severe acute hepatitis exacerbations if they stop taking this medicine. After quitting medication, hepatic function needs to be tracked for several months.
Side Effects
Tenvir side effects could include:
- Sickness
- Regurgitation
- Headache
- Dizziness
- Fatigue
- Rash
- Diarrhea
Among the harmful side effects are:
- Severe liver issues
- Lactic acidosis
- Issues with the kidneys –
- Reduced density of bone mineral
Patients should get in touch with their healthcare physician right away if they experience any serious adverse effects.
Storage and Handling
- Tenvir tablets must be stored at room temperature, between 20 degrees Celsius and 25 degrees Celsius.
- The tablets should be stored in their original container, tightly sealed, and kept away from direct heat and moisture.
- Ensure that pets and children cannot access the drug.
- The medicine should not be used after the expiration date on the container.
Conclusion
It is a key drug in the treatment of chronic hepatitis B virus (HBV) infection and HIV infection. Combining antiretroviral therapy with HBV management is crucial due to its ability to reduce viral levels and prevent the progression of these diseases. Patients who are advised of this drug should pay close attention to what their doctor says, take their medication as prescribed, and be aware of any possible adverse effects. Tenvir therapy must be monitored regularly and followed up medically to ensure its safety and efficacy.
FAQs
What should I do if I miss a dose of Tenvir?
As soon as you remember, take the medication if you forget to take it. If the time for your next dose is approaching, never combine two dosages at one go.
Can Tenvir be used during pregnancy or breastfeeding?
It may be harmful to the fetus hence, it should only be used during pregnancy if necessary and advised by the doctor. Pregnant women who test positive for HIV should talk to their doctor about the advantages and disadvantages. It is not at all recommended for HIV-positive women to breastfeed their children to stop the infection from spreading to them.
Where can I buy Tenvir?
When a licensed healthcare physician provides a valid prescription, most pharmacies in the United States sell Tenvir. You can buy it from arrowmeds.com, a trustworthy website. Make sure you are buying from a reliable source at all times. Tenvir Price can vary depending on the location and pharmacy.
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