Alternative Medicine

Azelastine/Fluticasone Propionate (Generic)

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Just $13 /Spray View Detail This product has multiple variants. The options may be chosen on the product page

Description

What is Duonase nasal spray

Duonase Nasal Spray contains two active ingredients: Fluticasone and Azelastine. It is primarily used to treat allergic rhinitis, runny nose, sneezing, watery eyes, and common cold symptoms. In some cases, it can also be used topically for skin problems such as dermatitis.

This spray is administered intranasally for effective relief and is available as an over-the-counter medicine under various brand names. Duonase is mainly used to manage respiratory allergies and certain skin-related conditions.

Uses of the Duonase nasal spray

• Runny nose
• Stuffy nose
• Sneezing
• Watery eyes
• Nasal congestion or stiffness

Usage Instructions:

• Blow your nose gently before use.
• Apply 2 sprays in each nostril as directed.
• Do not overuse, as it may worsen conditions or cause side effects.
• Do not share the spray with others, even if they have similar symptoms.

Preparation and Storage:

• Shake the bottle well before each use.
• Store in an upright position at room temperature.
• Dispose of the bottle properly after use.
• Replace the bottle after 100–120 sprays.

Dosage of Duonase nasal spray

• Consult a Doctor: Always seek medical advice before starting Duonase spray.
• Follow Instructions: Adhere to all precautions and guidelines provided by your doctor.
• Recommended Dose: Use 2 sprays in each nostril, twice daily.
• Preparation: Gently blow your nose before applying the spray.
• Avoid Eyes: Keep the spray away from the eyes to prevent irritation.
• Hygiene: Wash your face and hands thoroughly after each use.
• Do Not Overuse: Overuse may worsen symptoms or cause side effects.
• Do Not Share: Do not share your spray with others, even if they have similar symptoms.
• Storage: Keep out of reach of children and pets.
• Proper Disposal: Each bottle contains 100–120 sprays; dispose of the bottle properly after use.
• Before Each Use: Shake the bottle well and ensure the cap is tightly closed after application.

Benefits

• Duonase nasal spray carries two active ingredients, fluticasone and azelastine.
• Fluticasone belongs to the synthetic triflouronated corticosteroids class, serving anti-inflammatory functions.
• Azelastine belongs to the pthalazinone derivative class, which is an H1 receptor antagonist.
• It blocks H1 receptors and inhibits the release of interleukins and histamine, which are responsible for allergic reactions.
• Due to these properties, Duonase spray is used to treat runny noses, allergic rhinitis, stuffy noses, watery eyes, congestion, stiffness, and sneezing.
• It can be used as both an over-the-counter medicine and a prescribed medicine by doctors for specific advice and precautions.

What are the side effects of Duonase nasal spray

Always follow all precautions and preventive measures as prescribed and advised by the doctor.

During the application of Duonase nasal spray,  one can feel the following side effects-

• Nasal congestion
• Tingling sensations
• Pain in the nasal sinuses
• Fever
• Chills
• Body ache
• Redness
• Sores in throat and nose
• Bleeding from the nasal cavity
• Dryness and numbness in the finger
• Allergic or itching feeling in the eyes, glaucoma, when coming in contact with the eyes

Precautions

• Always consult your doctor before use and follow all prescribed instructions and precautions.
• Use with extra care in patients with somnolence, glaucoma, cataracts, visual disturbances, and in pregnant or breastfeeding women.
• Do not use if you have skin infections.
• Wash your hands and rinse your mouth thoroughly after using the spray.
• Keep the spray out of reach of children and pets.
• Store at room temperature in an upright position.
• Shake the bottle well before each use.
• Do not share your spray bottle with others.
• Dispose of the spray properly after use.
• Avoid applying Duonase to large areas, broken or damaged skin, wounds, or any ocular injuries.
• Not suitable for patients with asthma.
• Avoid use in case of primary cutaneous viral infections, such as herpes simplex or chickenpox.

What are the common drug interactions

The following drugs can interact and interfere with Duonase nasal spray. These are –

• Clarithromycin will lead to an increased level of the active component, fluticasone.
• Ritonavir- it is a CYP3A4 steroidal drug. Its use, along with Duonase spray, slows down liver processes.
• Ketoconazole- its use along with a nasal spray results in worsening of side effects.
• Phendimetrazine – results in decreased sedative and stimulatory action of Duonase spray.
• Nafcillin – it increases the metabolism of Duonase spray
• Moxifloxacin decreases the metabolism of active components of Duonase nasal spray.
• Methoxyflurane – it results in increased CNS depressant activity.
• Aceclofenac – results in an increased risk of GI bleeding
• Amoxapine – results in increased CNS depressant activity.

Buy Duonase nasal spray online

You can purchase Duonase nasal spray online by comparing different websites to find the most reliable option.

• Ensure that both the website and the product are authentic and secure.
• Verify that the sellers are reputable and trusted.
• Buy only from well-known and credible online pharmacies or brands in the US and UK.
• Look for competitive prices while ensuring the product’s effectiveness and safety.
• Online purchasing provides a convenient and fast way to get Duonase nasal spray without unnecessary delays.
• Access the official websites of trusted drugstores to order your product quickly and safely.

Frequently asked questions

What happens if you use too much Duonase nasal spray?

Always use Duonase nasal spray after consulting a doctor and following their advice. Do not overuse it. If a person overuses it, he/she may suffer from side effects like tingling sensations, itching on the face and in the eyes, bleeding in the nasal cavity, redness, sores in the nose and throat, fever, chills, body ache, and dryness in the face and hands. If you experience any of these side effects, contact your doctor immediately and stop its use until consultation is done.

What if you forget to use Duonase nasal spray?

Usually, it is used after consulting a doctor. There are no harmful signs or symptoms that will occur if you forget to use Duonase nasal spray.  So, do not worry about this. Continue its next use or application as soon as you remember about it. Use Duonase nasal spray 2 times a day in each nostril in the amount of two sprays. And also consult or ask your doctor for further use and information.

How does Duonase nasal spray work?

Duonase nasal spray contains two active ingredients: azelastine and fluticasone. Fluticasone is a synthetic triflouronated corticosteroid having anti-inflammatory activity. Azelastine belongs to the H1 receptor antagonist class. H1 receptors are a type of G-protein-coupled receptor that are present /available on nerve endings, smooth muscles, and gland cells. It inhibits the release of interleukins, histamine, and TNF-alpha, which are responsible for allergic conditions and hypersensitivity reactions.  So in this way, it is used to treat all types of rhinitis, runny nose, watery eyes, and sneezing.

How to use Duonase nasal spray?

Duonase spray was used after consulting a doctor. It is also available over the counter. Shake the spray bottle well before using it. Always administer through the intranasal route. It is used twice a day in each nostril, with 2 sprays per nostril. Keep it upright and cover it tightly after use. Keep it out of reach of children and pets. Dispose of it properly after use. Do not share your Duonase nasal spray with any other person having the same signs and symptoms as yours. Throw the nasal spray after using 100-120 sprays from the same bottle and dispose of it properly. Store it at room temperature.

How to store Duonase nasal spray?

Usually, follow all instructions and precautions as advised by the doctor. Keep it at room temperature. Cover it tightly after every use. Please keep it out of reach of children and pets. Properly dispose of it after use. Throw the nasal spray bottle after 100-120 sprays from it. After use or if it has expired, dispose of it properly. Wash your hands and mouth after every use.

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