Xovoltib 50mg

Xovoltib 50 mg (Afatinib Dimaleate)

Active Ingredient: Afatinib Dimaleate
Indication: Non-small cell lung cancer
Manufacturer: Boehringer Ingelheim India Pvt.Ltd
Packaging: 7 tablets in 1 strip
Strength: 50mg
Delivery Time: 6 To 15 days
10% OFF: Use Code AM10 @ Checkout page

Xovoltib 50 mg (Afatinib Dimaleate)

50mg Price Price/unit Quantity Add To Cart
28 Tablet/s $999 $35.68 /Tablet
56 Tablet/s $1800 $32.14 /Tablet
84 Tablet/s $2790 $33.21 /Tablet
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Last Updated on
Medically Reviewed by
Dr. Jack Williamson

Description

What is Xovoltib 50 Mg

Xovoltib 50 mg is a prescription medication containing the active ingredient Afatinib Dimaleate, which is used in the treatment of non-small cell lung cancer (NSCLC). It is typically prescribed to adult patients diagnosed with specific types of lung cancer. The medicine works by inhibiting the growth and multiplication of cancer cells, thereby helping to slow down or stop the progression of the disease.

Xovoltib 50 mg is manufactured by Boehringer Ingelheim India Pvt. Ltd., a well-known pharmaceutical company recognised for producing high-quality oncology medications. This medicine should be taken only under the supervision of a qualified doctor to ensure safe and effective treatment.

Uses Xovoltib 50 Mg

  • Xovoltib 50 mg is used to treat a specific type of cancer known as non-small cell lung cancer (NSCLC).
  • It is an FDA-approved prescription medicine containing Afatinib Dimaleate (50 mg), which belongs to a class of drugs called kinase inhibitors.
  • The medication is taken orally in tablet form.
  • Afatinib Dimaleate is prescribed for NSCLC that has spread to other parts of the body.
  • It is typically used as the first-line treatment in patients whose tumours have specific EGFR gene mutations.
  • It may also be recommended for patients with squamous NSCLC whose condition has worsened after chemotherapy.
  • Research is ongoing to explore other potential cancer treatments involving Afatinib Dimaleate.

Guidelines for the use of Xovoltib 50 Mg

Xovoltib 50 Mg tablet should be taken as directed by your doctor. Typically, Xovoltib 50 Mg, an oral route medicine should be taken with water on an empty stomach. Do not chew or crush the tablet; instead, swallow it whole with a glass of water. Xovoltib 50 Mg tablet dosage and duration will be determined by your doctor based on your age, weight, and medical condition.

How Does Xovoltib 50 Mg Work?

Xovoltib (Afatinib) 50mg works by inhibiting the activity of specific tyrosine kinase receptors in cancer cells. Its primary targets include the Epidermal Growth Factor Receptor (EGFR), HER2, and HER4, which are members of the ErbB family of proteins. Afatinib forms a covalent bond with these receptors, irreversibly blocking their kinase activity, which disrupts signalling pathways critical for cancer cell growth and survival. By preventing auto-phosphorylation and trans-phosphorylation in these receptors, Afatinib ultimately inhibits tumour proliferation and induces cancer cell death.

In simple words, In particular, Afatinib is effective against certain EGFR mutations that are common in non-small cell lung cancer (NSCLC). The drug’s inhibitory effects are also observed in cancer cells overexpressing HER2, making it useful for certain HER2-positive cancers. Afatinib broad inhibition of the ErbB family contributes to its effectiveness in various solid tumors.

Recommended Dosage (20mg, 40mg, 30mg, 50mg)

There are different dosages of Xovoltib, i.e. 50 mg, 40 mg, 30 mg, and 20 mg. Adults are typically advised to take 40–50 mg once a day. However, your doctor must determine the dosage for you. Doctors may also change the dosage in response to side effects or tolerance.

Overdose:

In case of a drug overdose, various kinds of symptoms or problems may arise. If they are serious, contact the doctor as soon as possible. Generally, people notice common or serious side effects more prominently in case of such an overdose. You may notice nausea, stomach pain, weakness, dizziness, vomiting, headache, etc.

Missed Dose:

If you miss any particular dose of Xovoltib 50 mg, first, do not panic. You should know that one missed dose is not too bad after all. You should take your missed dose as soon as possible. But remember the guidelines. If your doctor prefers to have it on an empty stomach, that should be maintained.

Potential Side Effects of Xovoltib 50 Mg

There might be some possible side effects of Xovoltib 50 mg. While common side effects are not a major concern, serious side effects may be a great cause of distress. Inform your doctor about the side effects immediately.

  • Nose bleeds
  • Dry skin
  • Loss of appetite
  • Itching
  • Sores in the corners of the mouth
  • Acne
  • Nail infection
  • Shortness of breath
  • Sensitivity to light
  • Rash
  • Cough
  • Fever
  • Nausea
  • Decreased urination
  • Vomiting
  • Excessive tiredness
  • Dark urine
  • Difficulty breathing
  • Diarrhea

Precautions and Warnings

While taking Xovoltib 50 mg you should follow certain precautions to be on the safer side. Be careful about the following situation:

  • If you are allergic to the drug Afatinib, you should avoid this medicine; otherwise, you may notice allergic reactions.
  • Inform your doctor about all your past medical history.
  • If you are already taking other drugs, inform your doctor.
  • You should avoid alcohol while taking this medication.
  • You may feel dizzy due to the effect of this drug. Hence you should be aware while driving after taking this tablet.
  • Before taking this medicine, you should let your doctor know if you have any existing lung, heart, kidney, or liver problems.
  • This drug may affect the patients during pregnancy or breastfeeding. Hence, a doctor’s counsel is necessary.
  • Since your skin may get sensitised due to the effect of Afatinib, try to avoid exposure to sunlight to the extent possible.
  • The non-prescription medicine known as St. John’s wort may interact with Afatinib; so be mindful of that.

Interactions With Other Medications

Interactions with other medicines can happen in the case of Afatinib. It may interact with the following drugs:

  • Itraconazole
  • Erythromycin
  • Ritonavir
  • Ketoconazole
  • Saquinavir
  • Nelfinavir
  • Amiodarone
  • Quinidine
  • Verapamil
  • Rifampicin

Conclusion

Xovoltib 50 mg (Afatinib) is a specialised treatment option for patients with non-small cell lung cancer (NSCLC) characterised by specific EGFR gene mutations. The drug has shown effectiveness as a first-line treatment and in cases where the cancer has progressed following chemotherapy.

Proper adherence to dosage guidelines, monitoring for side effects, and understanding potential interactions with other medications are critical for optimising the therapeutic benefits of Xovoltib. Patients should be under the careful supervision of a healthcare professional to ensure safe and effective treatment.

FAQs:

Who can take Xovoltib 50 mg?

Patients diagnosed with non-small cell lung cancer with specific EGFR mutations are eligible for Xovoltib. Your doctor will determine if this treatment is suitable based on test results.

What should I do if I miss a dose?

Stay calm if you forget to take a dosage.  As soon as possible, you should take the dose that you missed. But keep in mind the rules. You should follow your doctor’s instructions if they call for taking it empty-handed.

What should I avoid while taking Xovoltib 50 mg?

You should avoid alcohol and other drugs that may interact with Xovoltib 50 mg. See the interaction section above for detailed information about this.

How long will I need to take Xovoltib 50 mg?

The duration of treatment with Xovoltib depends on how well you respond to the medication and any side effects you may experience. Your doctor will regularly monitor your condition and adjust the treatment plan accordingly.

Where can I buy Xovoltib 50 mg?

Xovoltib 50 mg can be found online in The US. You may buy Xovoltib 50 mg online from a reliable seller, such as arrowmeds.com.

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