Alternative Medicine

Estradiol Valerate Injection (Generic)

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Just $2.33 /Ampoule View Detail This product has multiple variants. The options may be chosen on the product page

Progynon Depot (Generic) (Estradiol Valerate)

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Just $2.33 /Ampoule View Detail This product has multiple variants. The options may be chosen on the product page

Description

What is Estraval Depot Injection?

Estraval Depot Injection contains estradiol valerate, a synthetic ester of the natural hormone estradiol. This injectable medication serves as a natural estrogen replacement, the key female hormone responsible for regulating fertility and maintaining secondary sexual characteristics.

It is primarily prescribed to women experiencing menopausal symptoms or post-menopausal effects, such as hot flashes and vaginal dryness.

Estradiol valerate can be administered in several ways through vaginal application, oral tablets, or injections, with Estraval Depot representing the injectable form for effective hormone therapy.

Use of Estraval Depot Injection

Estraval Depot Injection finds its use in HRT or hormone replacement therapy and is a generic substitute for the estrogen hormone. Any female who suffers from a lack of estrogen hormone or those suffering from the aftermath of menopause, during which estrogen levels in the body may drop, resulting in a lack of female sexual features, may also use the Estraval Depot Injection.

This medicine, in its injectable version, is also helpful for patients as a subsidiary form of treatment in curing prostate cancer due to hypogonadism and primary ovarian failure.

It has the following major uses-

• Hormonal replacement therapy for the estrogen hormone

HRT is a way of replacing the shortfall of estrogen hormone levels in females, which is common during the onset or after menopause. It can create symptoms such as night sweats, hot flashes, and vaginal dryness. The symptoms are also common after undergoing surgical procedures that remove the ovaries.

• Postmenstrual osteoporosis

Taking in the Estraval Depot Injection can also help in curing postmenopausal osteoporosis or bone density loss common in females after menopause.

• Inducing transgender hormone cure

Estraval Depot Injection Online can also help those persons or transgender individuals who want to induce female features in themselves.

• Regulating menstrual disorders caused by hormonal imbalance.
• Supporting fertility treatments, especially in cases of estrogen deficiency.
• Treating ovarian failure or hypogonadism, where the body does not produce enough estrogen naturally.

Benefits of Estraval Depot Injection

Estraval Depot Injection offers several important health benefits, particularly for women experiencing hormonal imbalance or estrogen deficiency. The main benefits include:

• Hormone Replacement Therapy (HRT): Helps restore normal estrogen levels in women who have reduced natural estrogen production, such as during menopause.
• Relief from Menopausal Symptoms: Effectively reduces hot flashes, mood swings, vaginal dryness, and night sweats.
• Bone Health Support: Helps prevent osteoporosis and maintains bone strength in postmenopausal women.
• Improved Reproductive Health: Aids in regulating menstrual cycles and managing hormonal disorders such as ovarian failure or hypogonadism.
• Enhanced Overall Well-being: Promotes better skin texture, mood stability, and overall vitality by maintaining hormonal balance.
• Prostate Cancer Management: In men, it can be used as part of therapy to help reduce testosterone levels, which may slow the progression of prostate cancer.

What are the components that you will find in the Estraval Depot Injection?

Estrella Depot injection has estradiol valerate in the form of a sterile oil solution.  It is applicable for injection into intramuscular sites.

The Estrella Depot injection works as a precursor to the 17 beta-estradiol, which is the chemical form of the natural female estrogen hormone. It will bind to the estrogen receptor cells and is responsible for the maintenance of sexual characteristics in females.

How does Estraval Depot Injection work?

The working principle of the Estraval Depot Injection is dependent on the main generic component in it, which is estradiol valerate. When it is injected in the right amounts, this will work gradually and not overnight.

Carefully administering each dose will gradually work to increase the levels of the female hormone, estrogen.

The generic substance inside that is estradiol valerate will bind to the estrogen receptor cells and work to reduce the deficit levels of estrogen hormone in the female or transgender body.

How Should Estraval Depot Injection Be Used?

Estraval Depot Injection should be used strictly under medical supervision and only as prescribed by your doctor. This medication is given as an intramuscular injection, usually administered by a qualified healthcare professional in a hospital or clinic setting.

• Dosage frequency: For most women undergoing hormone replacement therapy, the injection is given once every 4 weeks.
• For prostate cancer treatment: It may be administered once every 2 weeks, as directed by the doctor.

If your doctor allows you to self-administer the injection at home, follow these precautions:

• Always check the vial for any particles or discoloration before use. Do not inject if the liquid appears cloudy or has visible particles.
• Inject only into the recommended intramuscular site using sterile equipment.
• Store the medicine properly at the temperature mentioned on the label. Avoid freezing, as very low temperatures may cause crystal formation. If crystals appear, gently warm the vial to return the liquid to normal.

Always consult your healthcare provider before adjusting the dose or frequency of Estraval Depot Injection.

Side effects to know about Estraval Depot Injection

Side effects may vary in intensity depending on the patient’s ability to tolerate the dose. The common side effects of the Estreval Depot injection include-

• Swelling of hands and feet
• Dark urine color
• Yellow skin and eyes
• Lump formation in the breast
• Nausea
• Vomiting
• Vaginal bleeding
• Itching
• Irritation
• Rashes
• Mood changes
• Coughing up blood
• Fainting
• Chest pain
• Abdominal pain
• Breathing difficulty
• Slurred speech
• Vision changes
• Severe headache
• Weakness in joints
• Insomnia
• Changes in liver function
• Dementia or loss of memory

Warnings and Precautions to know about using Estraval Depot Injection

Before starting Estraval Depot Injection, it is important to inform your doctor about your personal and family medical history, especially if there have been cases of cancer. Also, mention any known allergies, particularly to estradiol valerate or other hormonal medications.

Avoid taking contraindicated drugs such as anticonvulsants, rifampicin, rifabutin, or penicillin, as these may interfere with the effectiveness of estradiol.

If you are diabetic, use this injection with caution, as estradiol may alter blood glucose tolerance levels, potentially requiring adjustments in diabetic medication.

Smoking and excessive tobacco use can increase the risk of blood clot formation, so it is advisable to avoid these habits during treatment. Additionally, prolonged exposure to sunlight may cause dark pigmentation (melasma) on the skin, so protective measures should be taken.

Best storage conditions for Estraval Depot Injection

The ideal storage conditions are within a temperature range of around 15 to 25 degrees Celsius, with a maximum of 10 to 30 degrees tolerance levels. Avoid highly humid conditions, too. Storing them in the refrigerator might freeze the medicines, so keep them at a normal room temperature in your house.

FAQs

What might happen if you miss your dose of Estraval Depot Injection?

The Estraval Depot Injection will work only when you take the recommended doses at the frequencies as given by your doctors every few weeks. Do not forget to take your medicine after the fixed time interval between two successive doses.

Remember that if you miss your dose, then the medicine will have less efficacy, and generally, the effects will not show up as you think they will.

Possible causes of taking an excess dose of Estraval Depot Injection

It is very common for patients to overdose on even the slightest mistake. Avoid taking an overdose as this will not cure problems of estrogen hormone deficiency early, but rather, this will only trigger side effects.

What is the daily dose of Estraval Depot Injection?

This medicine is available in medicine shops or online websites in sets of 10 ampules or vials in one packet. The drug strength of each vial has an equivalent dose of 10 mg of estradiol valerate in every milliliter of the liquid.

Each vial needs administration generally after 4 weeks. This means that one pack of doses will last for well over the next few months

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