PDE-5 Inhibitors – Perfect Medicines to solve ED medicines


Define PDE-5 inhibitors and their significance in ED treatment.

PDE-5 inhibitors fall into different groups of medications that impede various types of chemical agents in the blood. Such assists blood vessels, which will relax and lessen irritation, etc. However, they are called and used for the treatment of erectile dysfunction or sexual problems. They are also widely utilized and associated with the circulatory system and heart.

On the other hand, PDE5 inhibitors help enhance the soft muscle cells that can stretch in gaining more and more erections while having sex. The absence of PDE5 inhibitors can directly affect the corpus cavernosum with a smooth muscle relaxing point. PDE5 inhibitors are the top medicine that mainly causes relaxation and widening of blood vessels, boosts blood circulation, and reduces blood pressure immediately. It is best known for treating other health conditions, which also leads to joint and skin treatment along with lung and heart conditions that can be cured, and then it simply eliminates sexual disorders. Furthermore, the conditions with joints and skin will be removed, and even sexual troubles can be cured.

PDE5 is an enzyme and molecule that assists chemical substances, which will occur faster and quicker than usual. Such PDE5 is available to certain people, with numbers given to every type to inform one side. 

PDE-3: Such type of PDE is particular to your heart and circulatory system. This way, it plays a role in having blood clots.

PDE-4: Such type is also particular to your lungs, which will occur and cause muscles in your airway system, mainly your bronchitis channels, to narrow and constrict.

PDE-5: This exists in the lungs and in a penile site that can be allocated to the male sex at birth.

Phosphodiesterase or PDE inhibitors are medicines that can obstruct enzymes, and these PDE inhibitors come with a choosy option that focuses on a particular PDE5. Other PDE5 inhibitors are non-selective.

What is erectile dysfunction?

Erectile dysfunction is a sex issue in which people will be unable to get erected with partners. This condition is generally cured with erection problems together with erectile dysfunction, which is a condition of sexual difficulties so that people cannot easily cope with sexual intercourse even as people are unable to deal with better sexual performance in life.

However, sexual abilities will not be resolved as impotence is an issue, so the individuals will not be able to have sex. No person can attain and sustain erections to the maximum levels; therefore, sexual intimacy will not happen with your partners.

On the other hand, you can spoil your sexual relationship because erectile problems will be badly affected by your lifestyle. Your lifestyle will be completely ruined when you will suffer from erectile dysfunction condition. Thus, when you are in the pain of ED, never give up trying various recommended ED medicines.

Common PDE-5 Inhibitors

There are four significant types of PDE5 inhibitors such as:

Sildenafil: Sildenafil was one of the primarily investigated PDE5 inhibitors and was approved by the FDA in 1998; it also comes by the name of Viagra and helps in curing erectile dysfunction among people. However, such Sildenafil usually takes steps in an hour. However, other PDE5 inhibitors can achieve an erection while sexually stimulated. It lasts for 4 hours and must be consumed around 25 to 100 mg daily as directed by doctors.

Tadalafil: Tadalafil is another important PDE5 inhibitor in the market, founded in 2003 to cure ED conditions. The medication is generally taken just 30 minutes before the sexual arousal process and within half an hour just before sexual activity. It is an FDA-approved medication that helps eliminate sexual problems quickly and performs long-lasting effects around 24 to 36 hours, so a regular dose is taken up to 2.5 to 20 mg daily.

Vardenafil: Vardenafil is also certified as a PDE5 inhibitor in the year 2003 that helps in curing impotence or ED conditions. It provides a minor beginning of PDE5 inhibitor that begins its long-term effects in 15 minutes and lasts 12 hours. A typical dose of medicine should be taken around 5 to 20 mg daily. 

Avanafil: Avanafil is one of the latest PDE5 inhibitors certified in 2012. It is one of the top PDE5 inhibitors that usually starts its mechanism within 45 minutes and lasts 5 hours. The medication should be used around 50 to 200 mg per day.                                                   

Dosage and Usage

The dosage of PDE5 inhibitor drugs is instructed to be consumed not more than once a day. Regular doses of ED medication must be taken before eating.

Dosage of medicine should be initiated for consumption just before being involved in sexual performance with your partners. This medicine needs to be taken without missing and overdosing.

Effectiveness and Safety

  • No other drugs or medicines should be taken when you use PDE5 inhibitors.
  • Drinking alcohol and smoking should be left.
  • Drink plenty of water in a day.
  • Take proper sleep every day.
  • Exercise is avoided after medicine consumption.
  • Go for regular walks and perform yoga when you are under treatment for ED.

Consultation with a Healthcare Provider

The most vital point to remember is to contact healthcare experts regularly and frequently. Before taking or starting their ED medications, patients should consult a doctor and get proper advice from their healthcare advisors about the treatment process and medicine’s direction.

Alternative and Complementary Treatments

Other alternative treatments for ED problems are regular taking of male-enhancing medications such as Cenforce, Fildena, and Vidalista drugs, which act superbly as PDE5 inhibitors, and provide the speediest form of ED treatments in the best possible ways.


With the quick process, the ED treatment is provided to the people that will give you the best possible way to cure your sexual condition immediately and quickly. Once you find the right solution for ED condition treatment option, it is best to take the right PDE5 inhibitor drugs or medication regularly.

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