Vardenafil vs. Sildenafil vs. Tadalafil

Vardenafil vs. Sildenafil vs. Tadalafil

In the world of today, where mental, physical, and emotional issues are increasing, there has been an increase in erectile dysfunction too. Men today are unable to achieve erections due to either of these reasons. They need effective treatment and on-time treatment to regain their lost life and to gain their confidence when they are in bed next time. Now, various medications are available to provide effective treatment for the condition. But one must consult the doctor before using it. However, before you go ahead, it is better to have Vardenafil vs. Sildenafil vs. Tadalafil beforehand. It will help you to cross-question or get advice on the dose and the effect of it on your body.

This article focuses on bits and pieces of individual medications to understand those better, apart from Vardenafil vs. Sildenafil vs. Tadalafil. Continue to read ahead and get to know more.

Understanding Erectile Dysfunction

Erectile Dysfunction or impotence, it’s the condition wherein an individual persistently fails to achieve/maintain an erection. It generally happens due to improper blood flow to the penile area, which can happen due to varied conditions. It can be either psychological issues like anxiety, stress, performance anxiety, etc., or physical issues including diabetes, neurological disorder, cardiovascular diseases, some medications, lifestyle factors (smoking, obesity), etc. The condition can be faced by men, irrespective of their age, and this leads to unsatisfactory sexual performance.

The occurrence of ED can be a huge impact on sexual health. It can affect a man’s well-being. It can even lead to lower sexual satisfaction, decreased self-esteem, relationship strains, etc. This is why it is important to address the concern sooner, find the diagnosis (physical examination, screenings, tests, etc.), and get necessary treatment like changes in lifestyle, medications, counseling, or anything asked by the doctor. It will help maintain a healthy/fulfilling life.

What is Vardenafil?

Vardenafil (Vilitra) is an important ED medication. This prescription medicine belongs to the class of drugs called the PDE-5 inhibitor. It gets used primarily for the treatment of ED wherein a man is unable to achieve/maintain an erection for time enough to have satisfactory sexual activity. With the help of Vardenafil, one gets relaxed blood vessels of the penis (the dose helps to have increased cGMP), which helps to have increased blood flow, resulting in the improved functionality of the penis.

The dose would show its effect for up to 4 to 5 hours. But note that the dose wouldn’t show any results if the medicine user is not sexually stimulated. It is because the dose isn’t the solution to having an automatic erection. It just helps to enhance sexual stimulation’s physiological response. Further, take the dose as prescribed and do not change the strength of the medication unless otherwise advised by the doctor.

The Role of Sildenafil in Treating Erectile Dysfunction

Sildenafil (Cenforce) is one of the PDE-5 inhibitors which is helpful in the treatment of erectile dysfunction. It works to inhibit PDE-5 enzymes that degrade the cGMP within the penis. With the blocking of such enzymes, the dose helps the body to have an increased cGMP level. This, in turn, helps to promote smooth muscles and better blood flow within the penis when the user of the dose is sexually stimulated. It helps to have better blood flow which helps the user achieve and maintain an erection.

The dose of Sildenafil has got extensive study. It has proven to remain effective within ED treatment. Even the clinical trials show significant improvement in the condition of ED in the men who suffered due to it before the dose. However, the dose wouldn’t cause an automatic erection. It would just enhance the natural erectile response to sexual stimulation. Further, do not worry when taking the dose, as this is well-tolerated and safe.

Tadalafil: A Long-Lasting Solution

Tadalafil (Vidalista), also known as the weekend pill, it is used for ED and benign prostatic hyperplasia. It is highly preferred as it provides a longer duration of action, i.e., 36 hours. It is this benefit of the dose which is known to set it apart from other ED medications. Further, the dose starts to show effect just one hour after its ingested. Onset action varies based on individual factors.

Sexual stimulation is a necessity for the dose of Tadalafil to show its effect and to help produce an erection. With prolonged erection, the dose provides flexibility and better spontaneity within the sexual activity. Therefore, the users do not have to plan any sexual encounter to ensure that they can achieve it within 4 to 5 hours after the dose has been taken. Now, if this wouldn’t help to enhance the sexual experience, then what would?

Key Differences between Vardenafil, Sildenafil, and Tadalafil

Some of the key differences in the three available erectile dysfunction medications are mentioned below.

Basis of DistinctionVardenafil Sildenafil Tadalafil
Duration of the action4-5 hours4-6 hoursUp to 36 hours
Action onset45-50 minutes45-50 minutes30 minutes to 1 hour
Timing FlexibilityMore precise as the medicines must be taken closer to the time when one wishes to initiate sexual activity.More precise as the medicines must be taken closer to the time when one wishes to initiate sexual activity.Better flexibility because of the longer duration of action. It allows users to have a spontaneous approach towards sexual activities.
Strength of Dose2.5mg-20mg25mg/50mg/100mg2.5mg/5mg/10mg/20mg
Daily useTaken on demand, for a time closer to when one is willing to initiate sexual activity.Taken on demand, for a time closer to when one is willing to initiate sexual activity.Can get prescribed for everyday use. It would allow sexual activity spontaneously, without any timing issues.

Factors to Consider When Choosing an Erectile Dysfunction Medication

As the individual response to the dose of medication varies, it is important to choose a PDE-5 inhibitor with proper consultation with the healthcare professional. Some factors, including personal choices, medication timing, accessibility, cost, side effects, body’s tolerance, available dosage, underlying health conditions, duration of the action, lifestyle, dose effectiveness, etc., are to be considered. Further, it would also be essential to follow the doctor’s prescribed dose to avoid any concerns.

Common Side Effects of Vardenafil, Sildenafil, and Tadalafil

Some common side effects associated with the use of Vardenafil, Sildenafil, and Tadalafil are,

  • Headache
  • Flushing
  • Nasal congestion
  • Dizziness
  • Lightheadedness
  • Indigestion or any other gastrointestinal symptoms
  • Visual disturbances
  • Back pain
  • Muscle aches, etc.

The above-mentioned isn’t an exhaustive list of the side effects. Individual experiences, always vary. So, if you have any questions or concerns related to the side effects of the dose of Vardenafil, Sildenafil, and Tadalafil, consult your healthcare professional.

Drug Interactions and Precautions

The dose can interact with some medication, food, or medical conditions. This is why it is better to let the doctor know about it all. To avoid drug interactions, the users of the PDE-5 inhibitors must avoid nitrates for chest pain, medications that can lower blood pressure, and the alpha-blockers which remain available for high blood pressure.

Some important precautions to consider when taking the dose to avoid interactions or any kind of side effects/altered effects are,

  • Avoid alcohol.
  • Do not take the dose if you are on nitrates.
  • Do not drive.
  • Do not take the dose without consulting the doctor if you have any kind of liver or heart, or kidney issues.
  • Avoid any other ED medication if you are already taking one.
  • Let the doctor know about all the medications you are on and your complete medical history too.
  • Do not take the dose if pregnant/breastfeeding.
  • The dose must be taken at least 1 hour before the sexual activity.
  • If the erection persists for more than 4 hours after the intercourse, you better seek medical attention.

Dosage and Administration Guidelines

The dose and the administration guidelines of all three medications are almost the same. But then, there are certain differences that one must remain aware of. A discussion of the same has been made below,

  • Vardenafil- the dose starting strength must be 10 mg, and it can be adjusted based upon the individual response as well the tolerance of the body. The max dose which can be recommended is 20mg in 24 hours. Just consume the tablet with water and take a dose with/without food, as per the doctor’s advice.
  • Sildenafil- the dose starting strength must be 50 mg, and it can be adjusted as per tolerance and individual response. Max dose in 24 hours that can be taken is 100mg. Take the medicine on an empty stomach. It helps to have faster absorption.
  • Tadalafil- The dose must be taken on-demand, and the starting dose strength must be 10mg (2.5mg in case of daily dosing). One can go to 20 mg (5mg for daily dosing) strength of the dose, max in a day. The dose can be taken without/with food but with water. Also, take the dose at the same time every day to ensure better effectiveness.

Comparing the Cost of Vardenafil, Sildenafil, and Tadalafil

Vardenafil vs. Sildenafil vs. Tadalafil is important, and price is one important factor. The price of the dose can vary based on discounts offered, pharmacy, location, insurance coverage, etc. The price might even vary based on the online/offline purchase.

In general, the dose costs are,

  • Vardenafil- $10-$30 for branded version and $1-$5 for generic dose.
  • Sildenafil- $10-$50 for branded version and $1-$10 for generic dose.
  • Tadalafil- $20-$70 for branded version and $1-$10 for generic dose.

Which Medication Is Right for You?

Which medication would be right for you? It cannot be decided unless, otherwise, you have contacted the doctor. The doctor accounts for varied factors that have been discussed in the above sub-heads before deciding on the dose or the strength of the same. So, it is advised not to self-medicate and consult the doctor before beginning the medicine course.

Consult Your Doctor

Make sure you consult the doctor before you begin the course of any medication. To have Vardenafil vs. Sildenafil vs. Tadalafil might look helpful, but you don’t know what your body can tolerate or whether or not you are allergic to the use of the PDE-5 inhibitor. So, go ahead and connect with the doctor today. Let them know about your entire medical history and all the medicines you are using. It will help avoid altered or side effects and will help receive the best benefits with the dose.


So, now that you already know most about Vardenafil vs. Sildenafil vs. Tadalafil, it is time to consult the doctor. It will help you to find out the underlying reason for the ED and will help you to receive the treatment on time. Further, with timely treatment, you will have the chance to stop your relationship from ruining. You would also have the chance to regain the lost confidence and be you.

Do not delay. Consult today and make your life better.

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