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Description
Introduction of Combutol 400mg
Combutol 400 mg is an antibiotic medicine that is used for the treatment of Tuberculosis (TB), which is an infectious disease caused by a bacterium called Mycobacterium tuberculosis. This disease affects the lungs and can also attack other body parts such as the spine, brain, and kidney.
It is available in tablet form and belongs to anti-tuberculosis drugs. Doctors prescribe this medicine to patients with at least one other tuberculosis medicine for effectiveness and better results. This antibiotic tablet treats only bacterial infections and will not work for viral infections.
The active ingredient of this Combutol 400 tablet is Ethambutol which disrupts the replication of Mycobacterium tuberculosis. Lupin Limited manufactures Combutol 400mg, driven by a strong commitment to advancing global healthcare.
Combutol 400 mg composition
Combutol contains Ethambutol hydrochloride of 400 mg as an active agent. Ethambutol prevents TB bacteria from multiplying and is used in combination with other antitubercular drugs for Tuberculosis treatment.
What is the use of Combutol 400 tablet?
Combutol 400 mg is given to those patients who are suffering from Tuberculosis. Doctor mainly prescribes this Combutol 400 tablet for the treatment of Tuberculosis affecting various organs such as:
- Pulmonary Tuberculosis, which mainly affects the lungs
- Tuberculous meningitis that affects the membranes around the brain
- Abdominal Tuberculosis
- Urogenital Tuberculosis affects the kidneys and bladder
- Re-treatment of Tuberculosis in cases when previous treatments have failed
- Prophylactic therapy for preventing the development of Tuberculosis in high-risk individuals.
This medicine has Ethambutol as an active ingredient, a bacteriostatic agent that is indicated along with other important medications such as isoniazid, rifampin, and pyrazinamide for treating pulmonary Tuberculosis.
How to use Combutol Tablet?
Combutol 400mg comes as a tablet to take orally. It is usually advised by doctors to take it once a day and to consume it at the same time every day. You can take it with you without food, but take it at a fixed time. Don’t crush or chew the tablet; swallow it whole.
Patients need to properly follow the directions and dosage given on their prescription by the doctor. Also, read the tablet leaflet instructions carefully. Don’t take more or stop the medication without consulting the doctor. This medicine is prescribed by the healthcare provider as a long-term medication and must be consumed daily.
What is the mechanism of action of Combutol 400 mg tablet?
Ethambutol is the main constituent of Combutol 400 mg tablet that works by stopping the growth of the bacteria that causes the disease. This medicine is the first line of Tuberculosis treatment given to the patients along with other medications such as rifampicin, INH, and pyrazinamide. Ethambutol is a bacteriostatic drug that interferes with the biosynthesis of arabinogalactan in the cell wall. This ultimately helps in stopping the multiplication of bacilli.
Other Dosages of Combutol
Side effects of Combutol 400 mg
Patients may feel some mild side effects of Combutol 400 which will go away in a few days. Serious allergic reactions or side effects of this medicine are rare, although one must seek medical help immediately if one observes any severe allergic reaction symptoms. It is common to experience issues like nausea or headache when you are on this medication. Tell your doctor immediately if any of these effects last longer or get worse.
Common Side Effects of Combutol 400 mg:
- Headache
- nausea/vomiting
- upset stomach
- loss of appetite
- eye problems like inflammation of the optic nerve
Uncommon side effects:
- Hyperuricemia, Which Causes High Levels Of Uric Acid In The Blood
Rare Side effects:
- Numbness
- low blood platelet count
- Allergic reactions such as rashes, itching, and swollen pale red bumps
- plaques (wheals) on the skin
Precautions and Warnings of Combutol 400 mg
- COMBUTOL 400mg is not given to pregnant women unless it is essential. So, it is advised to consult your doctor about your pregnancy or plans before taking it.
- Your doctor will give you the appropriate treatment after weighing the benefits and potential risks before prescribing it.
- Consult your doctor if you are a breastfeeding woman, as this tablet is generally not recommended.
- This antibiotic should be advised with care to patients with kidney disease. A dose adjustment of Combutol 400mg may be needed. Consult your doctor, as kidney function tests are recommended for patients before starting the medication.
- Liver problem patients should take Combutol 400 tablets cautiously. Consult your doctor before taking it to get the correct dose.
- For pediatrics and geriatrics:
- Combutol 400 tablets should not be for children below 13 years of age. It should be used with caution in children above 13 years of age after analyzing the health condition. Consult your doctor before taking in case of pediatrics.
- Patients above 65 years of age should consult the doctor before taking Combutol 400 mg tablet. Your doctor will cautiously prescribe the correct dosage depending on your age and health condition.
- Don’t drive or operate machines after taking Combutol 400 mg, as it might cause mild side effects like disorientation, dizziness, or tingling/numbness.
- Don’t take COMBUTOL 400 mg if you are allergic to Ethambutol or any of the other components of this tablet.
Conclusion
- Combutol 400 tablets should not be for children below 13 years of age. It should be used with caution in children above 13 years of age after analyzing the health condition. Consult your doctor before taking in case of pediatrics.
- Patients above 65 years of age should consult the doctor before taking Combutol 400 mg tablet. Your doctor will cautiously prescribe the correct dosage depending on your age and health condition.
- Don’t drive or operate machines after taking Combutol 400 mg, as it might cause mild side effects like disorientation, dizziness, or tingling/numbness.
- Don’t take COMBUTOL 400 mg if you are allergic to Ethambutol or any of the other components of this tablet.
Combutol 400mg is an essential anti-tuberculosis drug used in the treatment of Tuberculosis. This antibiotic medicine is prescribed to patients in combination with other antitubercular drugs. It works by stopping Mycobacterium tuberculosis from growing, hence eliminating the infection. Patients must follow the doctor’s given dose to ensure full recovery. Side effects of Combutol 400 mg are very mild but should be monitored in patients like pregnant women or those who have kidney or liver problems.
FAQs
When is the best time to take Combutol 400mg?
Patients can take this medication as a single dose daily at the same time as directed by the doctor.
What should I do if I miss a dose?
If you have missed the dose of Combutol, take it as soon as possible. But, if it is already time to take the next dose, do not take an extra dose to compensate for the missed one.
Can I drink alcohol while taking Combutol 400mg?
Don’t consume alcohol while taking Combutol 400 mg tablet, as it can slow down the medicine’s effectiveness and lead to liver injury.
Where can I buy Combutol 400mg?
Combutol 400mg can be bought from reputable online pharmacies like Arrowmeds.com. But make sure that you have a valid prescription to buy this medicine.
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